Will & Grace

Every straight girl needs a gay best friend, and interior designer Grace Adler found an ultimate accessory in her lawyer pal Will Truman. It's through this neurotic pair that the show's real stars -- Jack & Karen - come together. "Just Jack" McFarland and his boozy, pill-popping sidekick Karen Walker fill in the foursome that made Will & Grace classic TV and brought primetime to a whole new level of fabulous, while also winning 16 Emmy Awards in the process. With show-stopping guest appearances by Cher, Madonna, Britney, Janet, J-Lo, Ellen, Elton and most every gay icon under the sun, the milestones that Will & Grace hit provided a foundation for all LGBT portrayals on TV today.